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Tuesday, May 12, 2020 | History

3 edition of Adenosine and adenine nucleotides as regulators of cellular function found in the catalog.

Adenosine and adenine nucleotides as regulators of cellular function

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  • 25 Currently reading

Published by CRC Press in Boca Raton .
Written in English

    Subjects:
  • Adenosine -- Physiological effect.,
  • Adenine nucleotides -- Physiological effect.,
  • Cellular signal transduction.,
  • Adenine Nucleotides -- physiology.,
  • Adenosine -- physiology.

  • Edition Notes

    Includes bibliographical references and index.

    Statementeditor, John Whitfield Phillis.
    ContributionsPhillis, J. W.
    Classifications
    LC ClassificationsQP625.A27 A32 1991
    The Physical Object
    Pagination443 p. :
    Number of Pages443
    ID Numbers
    Open LibraryOL1861317M
    ISBN 100849369282
    LC Control Number90015182

    Adenine is said to be one of the most essential organic molecules for life. It is a purine and a major part of the genetic makeup of cellular life. Adenine - it helps form nucleotides. when combined with thymine, it produces a strand of DNA. chemical formula is C 5 H 5 N 5. Melt. point - °C ( °F)File Size: KB.   Adenosine signaling and function in glial cells. from released adenine nucleotides by a cascade of ectonucleotidases that adenosine is an important regulator Cited by:

    Adenine is a purine base. Adenine is found in both DNA and RNA. Adenine is a fundamental component of adenine nucleotides. Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose; it forms adenosine triphosphate (), a nucleotide, when three phosphate groups are added to adenosine. Adenosine triphosphate is used in cellular . Function. Adenine is one of the two purine nucleobases (the other being guanine) used in forming nucleotides of the nucleic acids. In DNA, adenine binds to thymine via two hydrogen bonds to assist in stabilizing the nucleic acid structures. In RNA, which is used for protein synthesis, adenine binds Chemical formula: C₅H₅N₅.

    Adenine Nucleotides in Cellular Energy Transfer and Signal Transduction: UNESCO (Molecular and Cell Biology Updates): Medicine & Health Science Books @ ce: $ Human subcutaneous fibroblasts (HSCF) challenged with inflammatory mediators release huge amounts of ATP, which rapidly generates adenosine. Given the nucleoside’s putative relevance in wound healing, dermal fibrosis, and myofascial pain, we investigated the role of its precursor, AMP, and of its metabolite, inosine, in HSCF cells growth and collagen : Carina Herman-de-Sousa, Ana Rita Pinheiro, Ana Rita Pinheiro, Diogo Paramos-de-Carvalho, Maria Adeli.


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Adenosine and adenine nucleotides as regulators of cellular function Download PDF EPUB FB2

FUNCTIONS OF PURINES AT THE CELLULAR LEVEL. Adenosine, Adenine Nucleotides and Platelet Function (N.J. Cusack and S.M.O. Hourani). Purines and Inflammation: Neutrophils Possess P1 and P2 Purine Receptors (B.N.

Cronstein). Adenosine and Immune System Function (T.S. Priebe and J.A. Nelson). Purinergic Regulation of Transmitter Release (J.A. Ribeiro). Adenosine and Adenine Nucleotides As Regulators of Cellular Function - CRC Press Book This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides.

Describes signaling and regulatory functions of adenosine and the adenine nucleotides. This book includes such topics as the historical development of research on adenosine and adenosine triphosphate, and the role of adenosine in the regulation of flow in different vascular beds.

Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels. Phillis JW(1). Author information: (1)Department of Physiology, School of Medicine, Wayne State University, E. Canfield, Detroit MIUSA.

[email protected] by: This book contains a selection of lectures given during the 5th International Symposium on Adenosine and Adenine Nucleotides, recently held in Philadelphia, Pennsylvania.

Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology covers a wide range of subjects from molecular and cellular biology to clinical : Hardcover. and adenine nucleotides. Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology is an excellent, up-to-date reference book for main and medical scientists inside the space of adenosine and adenine nucleotides.

How to Download Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology Pdf. cellular adenosine in other cellular and organ systems, including the brain, kidney, skeletal muscle and adipose tissue. Based on this evidence, a unifying hypothesis for adenosine action was formulated by Newby [4], and the term ‘retaliatory metabolite’ was coined to describe the protective function of adenosine.

Extracellular adenine nucleotides interact with P2-purinergic receptors to regulate a broad range of physiological processes.

These receptors include the P2Y- P2U- P2T- P2X- and P2Z-purinergic Author: David M Paton. Adenosine is an endogenous purine nucleoside that, following its release from cells or after being formed extracellularly, diffuses to the cell membrane of surrounding cells where it binds specific cell-surface structures that recognize it, termed adenosine receptors 1, are four types of adenosine receptor, all of which are members of the G protein-coupled family of receptors ().Cited by: MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein Kyoung-Sim HAN and Donald E.

AYER1 Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UTU.S.A. The MondoA–Mlx transcription complex plays a pivotal roleFile Size: KB. This book contains a selection of lectures given during the 5th International Symposium on Adenosine and Adenine Nucleotides, recently held in Philadelphia, Pennsylvania.

Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology covers a wide range of subjects from molecular and cellular biology to clinical applications. Abstract. Adenosine, a natural purine metabolite of adenine nucleotides, is a key regulator of many physiologic functions including vascular blood flow, platelet thrombotic activity, lipolysis and neurotransmission (1–3).Author: Kailash C.

Agarwal. Oxygen radicals and secreted proteases, in particular, are responsible for some aspects of neutrophil-mediated injury to endothelial cells and cardiomyocytes. A variety of neutrophil functions, including adhesion and reactive oxygen species production, are inhibited by adenosine (Ado) (Cronstein, and Cronstein, et al., ).Cited by: 4.

Adenosine, a nucleoside derived primarily from the extracellular hydrolysis of adenine nucleotides, is a potent regulator of inflammation. Adenosine mediates its effects on inflammatory cells Cited by: This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and.

of adenine nucleotides on epidermal cell prolifera­ tion. Our present study demonstrates that adenosine and its related nucleotides (ATP, ADP, AMP) are antiproliferative for nOrlllal human epidermal kera­ tinocytes cultured in the absence or presence of exogenous epidermal growth factor.

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Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology. Share your thoughts Complete your review. Tell readers what you thought by rating and reviewing this book. Rate it * You Rated it *Brand: Springer US. Opposing effects of intracellular vs.

extracellular adenine nucleotides on autophagy: implications for -cell function. Tal Israeli 1, Yael Riahi, Ann Saada2, Devorah Yefet 2, Erol Cerasi, ADK is a master regulator of intracellular adenosine level in all living cells (Boison, ).

ADA is also the main regulator of adenosine concentration in plasma which is involved in development of inflammatory response and cytokine production. Alteration in serum ADA activity has been reported in a broad range of diseases such as tuberculosis, HIV, lung cancer, chronic heart failure and chronic obstructive pulmonary disease (16 - 20).Cited by: 3.

Opposing effects of intracellular versus extracellular adenine nucleotides on autophagy: implications for β-cell function Tal Israeli 1, Yael Riahi, Ann Saada2, Devorah Yefet2, Erol Cerasi1, Boaz Tirosh3 and Gil Leibowitz1,* ABSTRACT AMPK–mTORC1 signaling Cited by: 1.Adenine nucleotides in RBCs contain adenine, ribose, and one or more phosphate groups.

Mature RBCs cannot synthesize adenine nucleotides de novo but can produce these compounds utilizing so-called salvage pathways (Brewer, ; Eaton and Brewer, ). AMP can be synthesized from adenine or from adenosine, both of which may be supplied to RBCs as they pass through the liver.

Adenosine is a product of complete dephosphorylation of adenine nucleotides which takes place in various compartments of the cell. This nucleoside is a significant signal molecule engaged in regulation of physiology and modulation of the function of numerous cell types (i.e. neurons, platelets, neutrophils, mast cells and smooth muscle cells in bronchi and vasculature, myocytes etc.).Cited by: